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By inhibiting NNMT and preserving NAD, 5-Amino-1MQ triggers a metabolic shift toward greater energy expenditure

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FIGURE 4 Surprisingly, cascades with TMLH, but lacking one or more (active) enzymes (combination C, D, E, F, and G) also showed L-carnitine biosensor signal output, albeit it was significantly lower than that of the complete cascade (combination H)

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