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A supervised taper over 48 weeks allows your brain to gradually increase satiety thresholds and your gut hormones to normalize more smoothly

Given that this is an investigational treatment, clinical trials are necessary to evaluate the efficacy and safety of the long-acting PYY analog, as indicated by the forthcoming Phase 1 SAD/MAD data expected in 2025

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Proprotein convertase subtilisin/kexin 9 inhibitors: an emerging lipid-lowering therapy

Adams C, Kopp M, Larburu N et al (2019) Structure and molecular mechanism of ER stress signaling by the unfolded protein response signal activator IRE1

Antipsychotic-induced weight gain: dose-response meta-analysis of randomized controlled trials