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STANDARDS FOR EVALUATING THE EFFICACY OF OBESITY TREATMENT DRUGS The mechanisms of action and structural formulations of GLP-1RA-based therapies for obesity are detailed in Figs

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Dry formulations are more resistant to temperature fluctuations and microbial contamination - providing a longer shelf-life, while still delivering all the benefits of a liposomal structure, which is activated when mixed with water

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Balancing these tangible costs against theoretical aspiration risks reinforces the need for pragmatic, patient-centered management rather than blanket cancellation policies

However, ONeil added an important caveat, reminding patients not to make too much of day-to-day gains or losses