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The MHRA-approved indication is weight management in adults meeting specific BMI criteria

Multivariate analysis revealed that the hepatic GLP-1R level was independently associated with hepatic steatosis (Table 1)

Whilst rare, these could indicate cardiovascular complications requiring immediate assessment

Consult your doctor if pregnant, nursing, or under medical supervision

These risk differences might be explained by additional mechanisms beyond the actions of GLP-1 RAs on vasculature, including the chronotropic effects of GLP-1 RAs which may blunt cardiac protection (Garg et al., 2019)

doi: 10.1007/s00125-010-2028-x 168 LiljedahlLPedersenMHMcGuireJNJamesP