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Severe gastrointestinal effects may occur with acute overdosage [10]

Given the high mean HbA1c values observed, additional oral agents, such as sodium-glucose cotransporter 2 inhibitors (SGLT2is), which have been demonstrated to reduce HbA1c by between 0.21 and 0.78% [17], would be unlikely to achieve glycemic goals of 9% was only about 25%, much less than the likelihood of achieving control when injectable therapy is started at a lower HbA1c

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MMP/TIMP Rebalancing