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A is neurotoxic and synaptotoxic, and it may also induce neuroinflammation by activating microglial cells

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Sulofenur [( N -(5-indanesulfonyl)- N -(4-chlorophenyl)urea, LY18664], the prototypic member of this class ( Figure 2C ), was evaluated in clinical trials on a variety of patients with kidney (Mahjoubi et al., 1993), ovary (OBrien et al., 1992), breast (Talbot et al., 1993), lung (Munshi et al., 1993), and stomach (Kamthan et al., 1992) cancers

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