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A consistent finding is reduced overall microbial diversity in AD, along with a phylum-level shift: the proportion of Firmicutes (typically beneficial fiber-degrading bacteria) tends to be decreased, while Bacteroidetes are increased [124]

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Moreover, in CD4 + T-cells, D5 stimulation activates ERK1/2, while D3 stimulation was linked to inhibition of this protein (Franz et al., 2015)

Using too much cream, mixing too many products, or expecting instant results can harm the skin

Week 1-4: Early Changes Most patients report subtle improvements in the first month, though the effects are mild

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