Journal of Clinical Biochemistry and Nutrition, 51 (2), 102107
In addition, as an NADPH-dependent coenzyme Q (CoQ) oxidoreductase, apoptosis-inducing factor mitochondria-associated 2 (AIFM2) can use NADPH to catalyse the regeneration of CoQ10 and act synergistically with GPX4 and GSH to inhibit phospholipid peroxidation and ferroptosis [77, 78]
In diet-induced obese mice treated with 5-Amino-1MQ for just 11 days, researchers observed a 35% decrease in white adipose tissue mass, a 30% decrease in adipocyte cell size, a 40% decrease in adipocyte volume, 50-70% reduction in lipogenesis, 30% lower total cholesterol, and no change in food intake
Using an MC38 colon adenocarcinoma model, the authors found H
Sun Y, Li J, Sun Y, Zhao R, Wang L, Song W, Wang Z, Wang J, Wei L, Zhao Y, et al
single-use aliquots are the standard laboratory practice to maintain experimental reproducibility