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First, by inhibiting system Xc , Erastin causes a drastic reduction in GSH levels, leading to the inactivation of GPX4 and the accumulation of lipid peroxides, thus inducing and amplifying ferroptosis

Imai and Guarente, 2014), an aspect that could worsen in these diseases because of its progressive nature (Cant et al., 2015)

PET imaging was conducted approximately 1 week after the operation, which showed local advancement of the lesion centered on the T5 vertebral body consistent with biopsy-proven malignant melanoma

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[1] Ill update this article as soon as details are available and the new prices are live