weight regain and cardiometabolic effects after withdrawal of semaglutide semaglutide: The STEP 1 trial extension PDF) Weight regain and cardiometabolic

Avoid alcohol: Alcohol is a potent trigger for nausea on semaglutide and can cause disproportionate blood sugar fluctuations

In August 2025, the first generic liraglutide for weight loss received full FDA approval and coverage for brand-name liraglutide dropped by nearly 90% following that approval

Risk factors for pancreatitis on GLP-1 medications include history of pancreatitis, gallstones, high triglycerides, and heavy alcohol use

Both Ozempic and Wegovy contain the same active ingredient, semaglutide , but they are approved for different medical purposes

February 18, 2026: Ozempic Manufacturer Runs $20 Million Super Bowl Ad Despite Mounting Lawsuits Novo Nordisk, which makes the GLP-1 drugs Ozempic and Wegovy, aired a high-profile ad during Super Bowl LX that reportedly cost more than $20 million

doi: 10.1001/jama.2023.19574