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One concern is that, if pre-cancerous cells are already present, very high availability of growth-supporting nutrients such as B12 could, in theory, support their growth too

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World J

Impaired individuals exhibit hypomethylation of CpG sites in the CCL11 promoter region, which are then hypermethylated upon supplementation with B12 In impaired individuals, three CpG sites exhibited hypomethylation when compared to the non-impaired group

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Individuals with Gastrointestinal Disorders Conditions such as Crohns disease, celiac disease, or those who have undergone weight loss surgery can affect the bodys ability to absorb B12