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JCI Insight (2018)
Aging of erythrocytes is associated with a wide array of structural, biochemical, and functional alterations, which facilitate clearance of senescent erythrocytes by phagocytic cells
This knowledge has led to the development of innovative products that can interact with these pathways, impacting hunger levels and the bodys ability to process food
A pure glucagon agonist, HM15136 (Hanmi Pharmaceutical) is in phase 1 trials
The paper takes advantage of the fact that some patients undergoing gastric bypass (GB) surgery experience significantly increased insulin secretion following a meal, sometimes even resulting in clinically significant hypoglycaemia
R.LitvinchukA.KhlJ.ZhengH
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