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Overall, the findings of the present study demonstrated that intra-articular stimulation of the liraglutide/GLP-1R axis has analgesic effects in vivo , which was probably due to the anti-inflammatory and anti-catabolic effects of liraglutide in vivo and in vitro, as demonstrated in vitro in macrophages and chondrocytes
The body receives a flat dose, processes it, and the negative feedback loop eventually suppresses endogenous production
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3) Antioxidant systems and ROS: the function of antioxidant systems in mitigating ferroptosis in OA warrants further investigation
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