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Among the most noteworthy are that Novo Nordisk manufactures both formulations and global supply shortages have affected the availability of both Wegovy and Ozempic

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Wegovy Injection: Initial dose (weeks 1 through 4): 0.25 mg subcutaneously once a week Dose escalation: Weeks 5 through 8: 0.5 mg subcutaneously once a week Weeks 9 through 12: 1 mg subcutaneously once a week Weeks 13 through 16: 1.7 mg subcutaneously once a week Alternatively: 1.7 mg subcutaneously once a week Comments: Major adverse cardiovascular (CV) events include CV death, nonfatal myocardial infarction, or nonfatal stroke