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Compounded semaglutide introduces additional maintenance considerations

However, it's worth noting that participants in the OASIS 4 trial had prediabetes (a forerunner to type 2 diabetes)

However, this strategy is not universally effective, as the medication's long half-life means side effects can occur at any time during the week

Semaglutides appetite-regulating effects, mediated through GLP-1 receptors in the brain, help suppress appetite, reduce caloric intake, and improve adherence to dietary modifications (Blundell et al., 2017)

Some patients notice reduced appetite or early weight loss during the first few weeks