The gout got worse over time, and the swelling and stiffness made it hard to even hold a cup or write
In addition, retatrutide improved insulin sensitivity, decreased lipid levels, and reduced liver enzymes (ALT and AST) after 36 weeks of treatment
Allergic reactions Serious allergic reactions, including anaphylaxis and angioedema (severe swelling of the face, lips, throat, or tongue), have been reported with Saxenda since it came to market
Published trials of tirzepatide monotherapy (which activates both GLP-1 and GIP receptors) show 2022% weight loss versus 812% for GLP-1 alone over 68 weeks
for others it's a reason to pursue a different path
Underlying Medical Conditions Certain health issues can increase the risk of rebound weight gain, including sleep apnea, hormonal imbalances, or thyroid disorders