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In HG-induced HK-2 and HFD/STZ-induced C57BL/6 mice, Huangkui Capsules (HKC) ameliorated renal tubular lesions in DKD by inducing mitophagy through upregulation of STING1/PINK1 pathway [132]

Lifespan and healthspan extension by resveratrol and related dietary stilbenes: Mechanisms and potential

Here, we expressed the human GPR17 long isoform (hGPR17L) in GLUTag cells, a murine EEC line, and we used the GPR17 synthetic agonist MDL29,951 together with pharmacological probes and genetic approaches to quantitatively assess the contribution of GPR17 signaling to GLP-1 secretion

This personalization reduces side effect risk and optimizes long-term efficacy from the start

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This article examines the current evidence, appropriate dosing, safety considerations, and when professional medical advice is essential