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The use of anabolic-androgenic steroids (AAS) such as testosterone and its derivatives has been described extensively (Creado and Reardon, 2016, Pope, Wood, Rogol et al., 2014)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 346.Akashi Y.J., Palus S., Datta R., Halem H., Taylor J.E., Thoene-Reineke C

Interestingly, incubation of human skeletal muscle cells with serum obtained from these subjects after the intervention resulted in an increase in PGC-1 expression, AMPK and SIRT1 activity, and mitochondrial biogenesis

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Tesamorelin's visceral fat reduction is documented in large RCTs