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The intended effect, she said, is to push companies toward submitting their single strongest, most competitive idea per topic rather than hedging across multiple submissions

doi: 10.1146/annurev.immunol.22.012703.104635 21 OGarraA.BrittonW

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In multiple paradigms, animals given GLP-1 agonists reduced their substance intake by 40-60%, even when the substances were freely available

Specifically, it has been established that 50% to 70% of insulin secretion in response to oral glucose administration is due to the incretin effect [1]

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