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The reason Ozempic and Mounjaro are excluded is the same reason T2D patients are: both drugs carry a Type 2 diabetes FDA indication, not a weight-management indication

Supply shortages have also made access unpredictable

In addition, ILCs do not undergo thymic selection, clonal selection, or clonal expansion

63 Building on this approach, Pathway-Level Information Extractor (PLIER) further integrates biological priors, such as pathway and marker gene sets, to improve interpretability and separate biological variation from technical noise particularly valuable for aging muscle tissue, in which subtle transcriptomic shifts are challenging to resolve

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