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5.1.2 Hydroquinone Hydroquinone is a hydroxyphenolic natural substance that is widely used in melasma management (Gupta et al., 2006

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4.2 Effect of NPY on sympathetic nerve activity NPY can inhibit KCl-activated POMC neurons in a dose-dependent manner, thereby reducing sympathetic nervous system activity (77)

The peptide has also demonstrated interactions with the dopaminergic and serotonergic systems, with studies showing that BPC-157 can modulate the effects of dopamine-related agents in animal models and counteract some behavioural and neurochemical consequences of both dopamine agonists and antagonists (Sikiric et al., 2010)