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In addition, the use of valproic acid with or without other anticonvulsants may cause hepatotoxicity and increase plasma ammonia concentrations, leading to encephalopathy

Three mice completed all the procedures, and no mice died during [ 18 F]FB(ePEG12)12-exendin-4 PET/CT scans

J.LefevreM.et al (2009)

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Medications like anticoagulants/antiplatelets, cyclosporine, and any medication changed by the liver (like cytochrome P450 3A4), are also not recommended with berberine