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Similarly, in IBS, treatments like ROSE-010 show varying efficacy depending on gender, which limits generalizability and underscores the need for more personalized therapeutic approaches

As LDs sequester not only neutral lipids but also PUFA-containing phospholipids, these are not released into the fatty acid pool for re-esterification in membranes as observed in MS4A15 OE cells

Manufacturers rely heavily on them to fund innovation, marketing, and trade promotions

The trial base STEP (NEJM 2021), SURMOUNT (NEJM 2022), SURMOUNT-OSA (NEJM 2024) belongs to the compound, not the platform