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An early clinical trial in 13 patients with type 2 diabetes found that a single intravenous infusion of 1,000 mg of lipoic acid improved insulin-stimulated glucose disposal (i.e., insulin sensitivity) by 50% compared to a placebo infusion (57)

This action preserves membrane integrity and prevents the lethal cascade that ferroptosis triggers

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Because these patches are not standardized or FDA-approved, there are no consistent dosing or wear-time guidelines, which is one reason clinicians recommend caution