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This finding provides significant clues to further reveal the mechanism of EBV reactivation, which is of potential clinical value for gaining insights into the early diagnosis and treatment of EBV-associated diseases

This may indirectly lessen the oxidative stress brought on by the imbalance of adrenal hormones (110)

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Since it is suggested that p53, p16, p21 are directly related to the induction of senescence in chondrocytes ( IL-6 and -8 , which however were not detectable due to the low expression level