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Certain patients may feel very light nausea or stomach distress if taken on an empty stomach with any vitamin

Zepbound (tirzepatide) is an FDA-approved medication for chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity such as hypertension, type 2 diabetes, dyslipidemia, or obstructive sleep apnea

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Diabetes Care 41(12):25602569

However, this approach must be considered as an add-on rather than an alternative to the search for novel drugs