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Graphical Abstract Keywords Insulin resistance, Lipid metabolism, Metabolic dysfunction-associated steatotic liver disease, MASLD, Oxidative stress, Silent information regulator 1, SIRT1, Therapeutic targeting Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent chronic liver condition closely linked to metabolic abnormalities

Goat shows the highest level (17.00.9 U/g Hb ), whereas pig expresses a relatively low amount of 3.50.2 U/g Hb

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