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Evidence for the important role of oxidative stress in the pathogenesis of acne

Iatcu et al., 2024)

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Cell clustering mediated by the adhesion protein PVRL4 is necessary for alpha6beta4 integrin-promoted ferroptosis resistance in matrix-detached cells

Their multiple mechanisms of action, which include significant weight loss, improved glycaemic control, blood pressure reduction, anti-inflammatory effects and potential direct cardioprotective and vascular effects, target multiple pathophysiological pathways implicated in HF progression