In that 2024 study, patients with type 2 diabetes prescribed semaglutide had a 36-month NAION incidence of 8.9%, compared to 1.8% in patients taking non-GLP-1 diabetes medications
Although Zepbound is a newly approved medication it is expected to be more effective in regards to weight loss, while Mounjaro is more effective for diabetes
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Estrogen shifts, testosterone fluctuations, and the metabolic consequences of sustained caloric deficit all influence sexual function during this period
Practical considerations for lighter individuals include potentially stronger gastrointestinal side effects at each dose level, faster onset of appetite suppression, and the possibility that 4 to 8 mg may be your effective maintenance range rather than 12 mg