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In mice, signaling through D5 combined with increased D3 expression led to T h 1/T h 17 differentiation, which contributed to the persistence of gut inflammation (Contreras et al., 2016)

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IV use also carries documented risks, including liver and kidney strain and serious skin reactions in case reports, part of why India's drug regulator restricted its cosmetic injectable use in 2026

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Rosacea is a chronic inflammatory skin condition that primarily affects the central face