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PMID: 16006804

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Journal of Agricultural and Food Chemistry , 65 , 92179225

The pathway of PDHc-mediated oxidation of pyruvate to acetyl-CoA is diagrammed below: The PDHc is comprised of multiple copies of three distinct enzyme activities: pyruvate dehydrogenase (PDH, identified as the E1 component), dihydrolipoamide S-acetyltransferase, (DLAT, identified as the E2 component), and dihydrolipoamide dehydrogenase, (DLD, identified as the E3 component)

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Other work pairs it with growth factors in studies of tendon, ligament, muscle, and bone healing