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By Meta-analysis, Wei et al 69 found that GLP-1RAs reduced the risk of nine respiratory diseases, including COPD, compared to placebo

This should prompt re-appraisal of the role of KG in physiology and disease via mechanisms other than the KG-dependent DNA and histone demethylases

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In our model oxidative stress is represented by an elevated level of H 2 O 2 which induces many changes in one-carbon metabolism and the transsulfuration pathway