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Genetics and pathogenesis of inflammatory bowel disease

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As we age, our bodies become less efficient at producing these essential compounds, leading to a decline in overall health and wellness

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Consequently, GF mice exhibit reduced body mass and adiposity compared to normal mice, necessitate a greater caloric intake to sustain equivalent body weight as conventional animals, and require dietary supplementation with vitamins K and B due to their susceptibility to vitamin deficiencies 2,25

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The lower dose (100 mg vs 500 mg in standard reduced products) reflects the theoretically higher bioavailability of the acetylated form

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