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There is increasing interest in developing tripeptides with targeted therapeutic functions, particularly for applications in wound healing [36, 75, 92], as well as in cancer [60, 170], neurodegenerative [24, 173], and cardiovascular diseases [177, 178], and in the design of functional foods [179, 182, 188]
These are one of, if not the most rigorously studied class of peptides ever, with many large, placebo-controlled, randomized trials that followed over the past twenty years from the original GLP-1 drugs such as exenatide, approved by the FDA in 2005
Other injectable formulations may be compounded preparations used at the discretion of the prescribing physician
The animal data, however, has been remarkably consistent and genuinely promising: Tendon and ligament healing : In rat models of Achilles tendon rupture, animals treated with BPC-157 showed significantly improved biomechanical outcomes (including greater failure load and tissue stiffness) within 10 to 14 days compared to untreated controls
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