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Beta-3 adrenergic receptor knockout mice are unresponsive to the lipolytic effects of AOD9604

This might involve increased dosing (up to 1000-1500mg per injection), enhanced frequency (moving from once weekly to twice or three times weekly), or strategic combination with synergistic supplements to amplify glutathione's effects

doi: 10.1097/WNR.0000000000000803 107

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-Lipoic acid is a coenzyme