While the underlying mechanisms of memory loss and cognitive impairment in bipolar disorder remain uncertain, these data indicate that defects in CaMKK2-CaMK1 signalling may play a role
As the mechanism of ferroptosis has been studied, many specific inhibitors of ferroptosis have been identified, including ferrostatin-1(Fer-1), liproxstatin-1, and vitamin E, as well as iron chelators, DFO, and deoxynivalenol methanesulfonate
To better elucidate a potential mechanism that would explain our findings, single-cell RNA sequencing should be considered for future work
Drugs in the GLP-1 receptor agonist class of medications work by mimicking the action of a hormone called glucagon-like peptide 1
Conversely, pathways enriched with downregulated DEGs encompassed PI3K-Akt signaling, calcium signaling, cytokine-cytokine receptor interaction, cell adhesion molecules, focal adhesion, phagosome, ECM-receptor interaction, cholinergic synapse, hematopoietic cell lineage, and malaria (Fig
[DOI] [PubMed] [Google Scholar] Jung HO, Tae-Jin L, Jong-Wook P, Taeg KK