However, it has also been observed that hormone-induced phosphorylation of serine 10 in H3 histone (H3S10) prevents the rapid remethylation of the preceding lysine, serving as the metronome of the process and giving the DNA damage repair system enough time to eliminate the oxidized nucleotides from nearby DNA 143
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To assess whether the level of ER stress, which is often coupled to mitochondrial dysfunction 34 , may be impacted by colistin treatment and rescued by co-incubation with L-carnitine, a staining against the ER stress marker GRP78/BiP was conducted
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