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Persistent nausea beyond 90 minutes or vomiting indicates the dose exceeded the subject's tolerance threshold

Intermediate users may increase the dose to 400500 micrograms daily

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Your weight If you are obese and have a higher body mass index, you may need tirzepatide treatment for a longer time and at higher doses (if your body tolerates it) compared to those with a lower body mass index or those who are a bit overweight

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