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SBIR does allow subcontracting to universities, labs, or consultantsbut within stricter workshare limits (67% in Phase I and 50% in Phase II must remain with the small business)

Other tests include patch tests, elimination diets, and oral challenges

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Lastly, ferroptosis can trigger systemic inflammatory response, activate multiple pro-inflammatory signaling, induce cardiomyocyte hypertrophy, fibrosis and death, and eventually lead to chronic adverse ventricular remodeling (Shirazi et al., 2017

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