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doi: 10.1016/S0140-6736(18)32260-8 112 FrasJPDaviesMJRosenstockJPrez ManghiFCFernndez LandLBergmanBKet al

In phase 2 clinical trials conducted in adult populations, retatrutide demonstrated substantial weight-loss efficacy, with reported reductions of up to 24.2% over a 48-week treatment period

Hum Immunol

For example, Wegovy , one of the most well-known GLP-1 medications, helped participants lose an average of 15% of their body weight when combined with healthy lifestyle changes

The STEP trials for semaglutide 2.4 mg in weight management showed mean weight loss of 14.9% from baseline at 68 weeks

This approach often produces healing outcomes that exceed what traditional post-operative care alone can achieve