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Combining Zepbound with other weight-loss medications (prescription, over-the-counter, or herbal) should be avoided, as these combinations have not been studied for safety or efficacy

Mitchell BD, Fox BD, Viswanathan A, Mitchell AH, Powell SZ, Cech DA

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With zinc, vitamin B6 and vitamin B1

Supplementation may be indicated for individuals with dietary restrictions, certain health conditions, or increased nutritional requirements

Additionally, a study that administered vitamin B-12 to rats with a high-fat diet showed that the rats did not gain as much weight as their counterparts who didnt receive the vitamin