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Scientific Research Overview The GHK-Cu literature gives a particular impression: a naturally occurring human tripeptide with high-affinity copper-binding chemistry, identified in the early 1970s, developed across five decades through wound-healing, extracellular-matrix, copper-biology, and cosmetic-research arms, and present in both the research peptide market and the cosmetic ingredient market in substantial regulated use

A 12-week facial study on 71 women by Finkley et al

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10.1016/j.semarthrit.2025.152652 39 CoaccioliS.Sarzi-PuttiniP.ZisP.RinonapoliG.VarrassiG

However, no renal endpoint was predefined for assessment in this trial

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