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Skin Sensitivity (Dysesthesia): Around 20% of people on the 12 mg dose reported mild tingling or skin sensitivity

The drug should not be administered if the patient is going to skip the meal

Novel therapeutic approaches in diabetes

The maintenance frequency approach represents hybrid strategy where initial intensive treatment (daily application for 3-6 months) establishes improvements, then reduces to maintenance schedule (2-3 times weekly or every other day) rather than complete discontinuation

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Cancer Cell 2012;22:631-44