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The authors summarized recent mechanistic insights and disease-specific evidence across irritable bowel syndrome, inflammatory bowel disease, and neurodegenerative and psychiatric disorders, while critically evaluating emerging EV isolation and analytical technologies in the context of MISEV2023 guidelines

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Fermented foods, such as kimchi, sauerkraut, and yogurt, provide a source of hormetins through the presence of probiotics and bioactive peptides, but also through a complex array of other microbial metabolites that can act as signaling molecules to modulate host physiology 32

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