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Zepbound PA criteria mirror Wegovy in 2026, with the same BMI thresholds and 6-month program requirement

Table 1 provides a comprehensive overview of the characteristics of the most commonly used GLP-1 RAs [12, 20]

End dates will vary by state

Last, our model did not incorporate the effects of GLP1RA therapy on gastric pH

Additional trials are also underway in participants with type 1 diabetes targeting diverse pathways including oxidative stress, using nicotinamide adenine dinucleotide phosphate oxidase (Nox)-1/4 inhibitors, and the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway, using bardoxolone (NCT03366337, NCT03550443) [84, 85]

For these individuals, extra vigilance may be warranted