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Biochemical assays Lipid peroxidation (LPO) was assessed as thiobarbituric acid reactive substances (TBARS) in terms of formed malondialdehyde (MDA) according to a method described by Ohkawa et al

In this regard, the mitochondria-targeted SOD mimetic Mito-tempo has been shown to protect against APAP hepatotoxicity, while Tempo, which exhibits SOD activity but without its specific mitochondrial targeting, failed to protect against APAP-induced liver injury ( - generation in APAP hepatotoxicity

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In another the patient applied 0.375mL of 100mg/mL NAD and 0.25mL of lidocaine 2% into each nostril (a total of 75mg NAD+ for a single dose)