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Moreover, excessive fission disrupts mitochondrial membrane potential, causes mitochondrial damage, and impairs both cellular energy metabolism and iron homeostasis, further sensitizing cells to ferroptosis [56]
HO-1 is involved in the regulation of macrophage polarization and promotes the M1 state (pro-inflammatory) towards to the M2 state (anti-inflammatory)
Investigation of the therapeutic effect of Yinchen Wuling powder on Ccl4-induced hepatic fibrosis in rats by 1H Nmr and Ms-based metabolomics analysis
It is synthesized in every cell from the amino acids glutamate, cysteine, and glycine (Lu, Biochimica et Biophysica Acta , 2013)
A scoring system for the classification of beta-thalassemia/Hb E disease severity
In renal failure, perturbed intestinal microorganisms produce several metabolic products that can have an influence on the kidneys, including indoxyl sulfate, trimethylamine N-oxide, phenylacetylglutamine, and p-cresyl sulfate
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