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Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes

Microdosing is an alternative that involves taking a prescribed low dose

Moreover, the upregulation of GPX3 expression may confer protection to tumor stem cells against exogenous oxidative stress injury, thereby facilitating the maintenance of stemness characteristics in OCSCs

Repeated freeze-thaw cycles should be strictly avoided to preserve peptide integrity and ensure consistent experimental results

Metabolism also plays a critical role in altering immune cell responses, thus exacerbating cancer progression (134, 142)