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Acta Diabetol 2020;57:68996.ArticlePubMedPDF 7

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1 AUC values shown in this table were calculated directly from each participants concentration-time data using noncompartmental methods, and therefore differ from the model-based estimated mean AUCs reported elsewhere in the manuscript, which were obtained from linear mixed-effects models fitted on log-transformed AUC and back-transformed to the original scale (estimated marginal means)

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Additionally, p300/Tip60 acetylates histones, promoting an open chromatin state and enabling Foxp3 to more readily access the regulatory regions of its target genes [62]