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Factors to consider: Risk classification of the device: The risk classification of the device will determine the extent to which you can rely on foreign clinical data

Differential activation of the sympathetic innervation of adipose tissues by melanocortin receptor stimulation

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GLP-1 RAs ameliorate hepatic steatosis through improved insulin sensitivity, direct suppression of hepatic de novo lipogenesis through AMPK activation and SREBP-1c inhibition, and enhanced fatty acid oxidation through PPAR upregulation

Alfthan G, Aro A, and Gey KF (1997)